Disability Syndrome

Sjögren Syndrome and Work Disability.

Intellectual disability and epilepsy in down syndrome.

UNLABELLED Down Syndrome (DS) is the most common genetic cause of mental retardation, with a reported frequency of epilepsy between 1.4-17% (1). There is a paucity of data in the literature regarding epilepsy in Down syndrome and its relation to intellectual disability. OBJECTIVES The purpose of this article is to analyze the association of epilepsy in children with DS - frequency and type of...

When Asperger's syndrome and a nonverbal learning disability look alike.

CASE Joey was always an active boy. As an infant, he experienced severe colic. As a toddler, his pediatrician described him as “hyperactive and more impulsive than most children his age.” Joey walked at 12 months but was unable to successfully drink from a cup until 15 months. His parents reported that he spoke several clear words at 12 months and that his spoken language was always ahead of ot...

Motoric Cognitive Risk Syndrome: Association with Incident Dementia and Disability.

BACKGROUND It is important to examine the etiology of motoric cognitive risk syndrome (MCR) and its association with dementia and disability to obtain biological insights and to develop preventive strategies. OBJECTIVE This study aimed to examine the association of MCR with incidence of dementia and disability in a Japanese community-dwelling sample of older adults. METHODS Participants wer...

Early onset intellectual disability in chromosome 22q11.2 deletion syndrome.

Chromosome 22q11.2 deletion syndrome, or DiGeorge syndrome, or velocardiofacial syndrome, is one of the most common multiple anomaly syndromes in humans. This syndrome is commonly caused by a microdelection from chromosome 22 at band q11.2. Although this genetic disorder may reflect several clinical abnormalities and different degrees of organ commitment, the clinical features that have driven ...